To open a Pptx file on Mac, you'll need to download and install a compatible app. Microsoft PowerPoint is a great option, and you can find it in the Mac App Store. Once you've installed it, simply double-click the Pptx file to open it.
Alternatively, you can use Keynote, a free presentation app that comes pre-installed on Macs. To open a Pptx file in Keynote, just drag and drop the file into the Keynote app, or use the "File" menu to open it. Either way, your Pptx file will be up and running in no time!